GOT2 Antikörper (N-Term)

Produktnummer ABIN2781299

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-GOT2 Antikörper (ABIN2781299) detektiert spezifisch GOT2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für GOT2 Antikörper (N-Term) (ABIN2781299)

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GOT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GOT2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GOT2 Antibody - N-terminal region

Sequenz: VEMGPPDPIL GVTEAFKRDT NSKKMNLGVG AYRDDNGKPY VLPSVRKAEA

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GOT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GOT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43517-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GOT2 Antikörper (ABIN2781299)

Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." in: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

Tsai, Hong, Liou, Liao: "Association study of GOT2 genetic polymorphisms and schizophrenia." in: Psychiatric genetics, Vol. 17, Issue 5, pp. 314, (2007) (PubMed).

Details zu GOT2

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Andere Bezeichnung: GOT2

Hintergrund:

Background Information: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)

Alternative Symbols: KAT4, DEE82, KATIV, KYAT4, mitAAT

Protein Name: Aspartate aminotransferase, mitochondrial

Molekulargewicht: 45kDa

Gen-ID: 2806

NCBI Accession: NP_002071

UniProt: P00505

Pathways: Monocarboxylic Acid Catabolic Process