GOT2 Antikörper (N-Term)

Produktnummer ABIN2781299

Dieses Anti-GOT2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GOT2 in WB. Geeignet für Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd und Saccharomyces cerevisiae. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für GOT2 Antikörper (N-Term) (ABIN2781299)

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GOT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GOT2 Antikörper

Bindungsspezifität: N-Term

Sequenz: VEMGPPDPIL GVTEAFKRDT NSKKMNLGVG AYRDDNGKPY VLPSVRKAEA

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GOT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GOT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 430 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GOT2 Antikörper (ABIN2781299)

Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." in: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

Tsai, Hong, Liou, Liao: "Association study of GOT2 genetic polymorphisms and schizophrenia." in: Psychiatric genetics, Vol. 17, Issue 5, pp. 314, (2007) (PubMed).

Details zu GOT2

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Andere Bezeichnung: GOT2

Hintergrund: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ40994, kat4, kativ, mitaat, KAT4, KATIV, mitAAT
Protein Interaction Partner: FUS, UBC, NEDD8, MDM2, CDK2, CCL21, GLRX, GAPDH, APCS, AI837181, HDAC5, PSMD4, THOC7, ZDHHC6, GLUD1, HSPA8, PC, MDH2, CTNNBIP1, MPG,
Protein Size: 430

Molekulargewicht: 45 kDa

Gen-ID: 2806

NCBI Accession: NM_002080, NP_002071

UniProt: P00505

Pathways: Monocarboxylic Acid Catabolic Process