STEAP3 Antikörper (C-Term)

Produktnummer ABIN2781298

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STEAP3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd und Kaninchen.

Kurzübersicht für STEAP3 Antikörper (C-Term) (ABIN2781298)

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STEAP3 Antikörper

Bindungsspezifität: C-Term

Sequenz: VALVLSTLHT LTYGWTRAFE ESRYKFYLPP TFTLTLLVPC VVILAKALFL

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human STEAP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 498 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Andere Bezeichnung: STEAP3

Hintergrund: AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.
Alias Symbols: STMP3, TSAP6, dudlin-2
Protein Interaction Partner: UBC, SETD7, BAD, TPT1, BNIP3L, PKMYT1,
Protein Size: 498

Molekulargewicht: 56 kDa

Gen-ID: 55240

NCBI Accession: NM_182915, NP_878919

UniProt: A8K6E3

Pathways: Transition Metal Ion Homeostasis