HECTD2 Antikörper (C-Term)

Produktnummer ABIN2781287

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HECTD2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ratte, Saccharomyces cerevisiae und Zebrafisch (Danio rerio).Es wurde in 1 Publikation zitiert.

Kurzübersicht für HECTD2 Antikörper (C-Term) (ABIN2781287)

Target: HECTD2 (HECT Domain Containing 2 (HECTD2))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ratte, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HECTD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HECTD2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: HECTD2 Antibody - C-terminal region

Sequenz: TDLTIKYFWD VVLGFPLDLQ KKLLHFTTGS DRVPVGGMAD LNFKISKNET

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HECTD2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HECTD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43481-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HECTD2 Antikörper (ABIN2781287)

Sun, Wang, He, Sweeney, Liu, Brown, Balk, Lee, Kantoff: "MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A." in: Oncogene, Vol. 33, Issue 21, pp. 2790-800, (2014) (PubMed).

Details zu HECTD2

Target: HECTD2 (HECT Domain Containing 2 (HECTD2))

Andere Bezeichnung: HECTD2

Hintergrund:

Background Information: HECTD2 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Gene Name: HECT domain containing E3 ubiquitin protein ligase 2

Alternative Symbols: FLJ16050

Protein Name: Probable E3 ubiquitin-protein ligase HECTD2

Molekulargewicht: 88kDa

Gen-ID: 143279

NCBI Accession: NP_877497

UniProt: Q5RD78