HECTD2 Antikörper (C-Term)
Kurzübersicht für HECTD2 Antikörper (C-Term) (ABIN2781287)
Target
Alle HECTD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- TDLTIKYFWD VVLGFPLDLQ KKLLHFTTGS DRVPVGGMAD LNFKISKNET
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against HECTD2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human HECTD2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 776 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A." in: Oncogene, Vol. 33, Issue 21, pp. 2790-800, (2014) (PubMed).
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: "MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A." in: Oncogene, Vol. 33, Issue 21, pp. 2790-800, (2014) (PubMed).
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- HECTD2 (HECT Domain Containing 2 (HECTD2))
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Andere Bezeichnung
- HECTD2
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Hintergrund
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HECTD2 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Alias Symbols: FLJ16050
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 776 -
Molekulargewicht
- 88 kDa
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Gen-ID
- 143279
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NCBI Accession
- NM_182765, NP_877497
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UniProt
- Q5RD78
Target
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