Deltex Homolog 3 Antikörper (C-Term)
Kurzübersicht für Deltex Homolog 3 Antikörper (C-Term) (ABIN2781281)
Target
Alle Deltex Homolog 3 (DTX3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Dtx3 Antibody - C-terminal region
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Sequenz
- YEKYGTIVIQ YVFPPGVQGA EHPNPGVRYP GTTRVAYLPD CPEGNKVLTL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Dtx3. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43465-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))
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Andere Bezeichnung
- Dtx3
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Hintergrund
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Background Information: Dtx3 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Dtx3 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Dtx3 functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Gene Name: Deltex 3 homolog (Drosophila)
Alternative Symbols: mg310, Deltex3
Protein Name: Probable E3 ubiquitin-protein ligase DTX3
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Molekulargewicht
- 38kDa
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Gen-ID
- 80904
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NCBI Accession
- NP_109639
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UniProt
- Q80V91
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Pathways
- Notch Signalweg
Target
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