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NSMCE1 Antikörper (N-Term)

Dieses Anti-NSMCE1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NSMCE1 in WB. Geeignet für Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Ziege, Hund, Pferd und Zebrafisch (Danio rerio).
Produktnummer ABIN2781253

Kurzübersicht für NSMCE1 Antikörper (N-Term) (ABIN2781253)

Target

Alle NSMCE1 Antikörper anzeigen
NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

Reaktivität

Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Ziege, Hund, Pferd, Zebrafisch (Danio rerio)

Wirt

  • 18
  • 1
Kaninchen

Klonalität

  • 19
Polyklonal

Konjugat

  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NSMCE1 Antikörper ist unkonjugiert

Applikation

  • 18
  • 9
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    RPIYALVNLA TTSISKMATD FAENELDLFR KALELIIDSE TGFASSTNIL

    Homologie

    Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

    Produktmerkmale

    This is a rabbit polyclonal antibody against NSMCE1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human NSMCE1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 256 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

    Andere Bezeichnung

    NSMCE1

    Hintergrund

    NSMCE1 is a probable component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
    Alias Symbols: NSE1
    Protein Interaction Partner: UBC, EID3, SMC6, NDNL2, Ube2k, UBE2D2, NSMCE2, NSMCE1, NSMCE4A, SMC5, SUMO2, MAGEF1,
    Protein Size: 256

    Molekulargewicht

    28 kDa

    Gen-ID

    197370

    NCBI Accession

    NM_145080, NP_659547

    UniProt

    Q8WV22

    Pathways

    Positive Regulation of Response to DNA Damage Stimulus
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