NSMCE1 Antikörper (N-Term)
Kurzübersicht für NSMCE1 Antikörper (N-Term) (ABIN2781253)
Target
Alle NSMCE1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- RPIYALVNLA TTSISKMATD FAENELDLFR KALELIIDSE TGFASSTNIL
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Homologie
- Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against NSMCE1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human NSMCE1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 256 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))
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Andere Bezeichnung
- NSMCE1
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Hintergrund
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NSMCE1 is a probable component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
Alias Symbols: NSE1
Protein Interaction Partner: UBC, EID3, SMC6, NDNL2, Ube2k, UBE2D2, NSMCE2, NSMCE1, NSMCE4A, SMC5, SUMO2, MAGEF1,
Protein Size: 256 -
Molekulargewicht
- 28 kDa
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Gen-ID
- 197370
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NCBI Accession
- NM_145080, NP_659547
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UniProt
- Q8WV22
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
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