LNX1 Antikörper (C-Term)

Produktnummer ABIN2781236

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LNX1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen und Meerschweinchen.

Kurzübersicht für LNX1 Antikörper (C-Term) (ABIN2781236)

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LNX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LNX1 Antikörper

Bindungsspezifität: C-Term

Sequenz: SHREWDLPIY VISVEPGGVI SRDGRIKTGD ILLNVDGVEL TEVSRSEAVA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LNX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LNX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 632 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LNX1

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Andere Bezeichnung: LNX1

Hintergrund: LNX1 is a membrane-bound protein that is involved in signal transduction and protein interactions. LNX1 is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis.This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.
Alias Symbols: LNX, MPDZ, PDZRN2
Protein Interaction Partner: GRB2, TRIP13, ZCCHC10, ROPN1, NECAB2, PRR13, ZNF581, APIP, MEMO1, ZNF593, OSGIN1, NME7, OSBP2, DNPEP, ISCU, MTUS2, RUVBL2, NEK6, RFPL3, AIDA, GDI1, ROBO3, PBLD, LSM2, HOMEZ, TRIM54, AGTRAP, LGALS14, TRIM39, NXT2, ZFP64, POMGNT1, GOLPH3L, TRMT12, FAM118A,
Protein Size: 632

Molekulargewicht: 70 kDa

Gen-ID: 84708

NCBI Accession: NM_032622, NP_116011