CBLL1 Antikörper (C-Term)

Produktnummer ABIN2781231

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-CBLL1 Antikörper (ABIN2781231) detektiert spezifisch CBLL1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Zebrafisch (Danio rerio) und Schwein.

Kurzübersicht für CBLL1 Antikörper (C-Term) (ABIN2781231)

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBLL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CBLL1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CBLL1 Antibody - C-terminal region

Sequenz: PFTQPGGMSP GIWPAPRGPP PPPRLQGPPS QTPLPGPHHP DQTRYRPYYQ

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CBLL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CBLL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096292

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CBLL1 Antikörper (ABIN2781231)

Horiuchi, Kawamura, Iwanari, Ohashi, Naito, Kodama, Hamakubo: "Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33292-302, (2013) (PubMed).

Details zu CBLL1

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Andere Bezeichnung: CBLL1

Hintergrund:

Background Information: Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1, MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A, MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM].

Gene Name: Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1

Alternative Symbols: HAKAI, RNF188

Protein Name: E3 ubiquitin-protein ligase Hakai

Molekulargewicht: 55kDa

Gen-ID: 79872

NCBI Accession: NP_079090

UniProt: Q75N03