CBLL1 Antikörper (C-Term)
Kurzübersicht für CBLL1 Antikörper (C-Term) (ABIN2781231)
Target
Alle CBLL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- PFTQPGGMSP GIWPAPRGPP PPPRLQGPPS QTPLPGPHHP DQTRYRPYYQ
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CBLL1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CBLL1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 491 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33292-302, (2013) (PubMed).
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: "Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33292-302, (2013) (PubMed).
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- CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))
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Andere Bezeichnung
- CBLL1
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Hintergrund
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Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1, MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A, MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM].
Alias Symbols: HAKAI, RNF188
Protein Interaction Partner: DGCR6, SUMO1, UBC, CDH1, RNF2, YWHAQ, SFPQ, Cbll1, ESR1, CTTN, DOK1, SRC, CDC42,
Protein Size: 491 -
Molekulargewicht
- 55 kDa
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Gen-ID
- 79872
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NCBI Accession
- NM_024814, NP_079090
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UniProt
- Q75N03
Target
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