HOXB8 Antikörper (N-Term)

Produktnummer ABIN2781203

Der Kaninchen Polyklonal Anti-HOXB8-Antikörper wurde für WB validiert. Er ist geeignet, HOXB8 in Proben von Human, Maus, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Pferd und Schaf zu detektieren.

Kurzübersicht für HOXB8 Antikörper (N-Term) (ABIN2781203)

Target: HOXB8 (Homeobox B8 (HOXB8))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXB8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HOXB8 Antikörper

Bindungsspezifität: N-Term

Sequenz: MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH

Homologie: Cow: 79%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXB8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 243 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HOXB8

Target: HOXB8 (Homeobox B8 (HOXB8))

Andere Bezeichnung: HOXB8

Hintergrund: HOXB8 is a member of the Antp homeobox family and is a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. HOXB8 functions as a sequence-specific transcription factor that is involved in development. Increased expression of this HOXB8 gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
Alias Symbols: HOX2, HOX2D, Hox-2.4
Protein Interaction Partner: PBX3, PBX2, PBX1, MEIS1,
Protein Size: 243

Molekulargewicht: 28 kDa

Gen-ID: 3218

NCBI Accession: NM_024016, NP_076921

UniProt: P17481