FOXM1 Antikörper (Middle Region)

Produktnummer ABIN501829

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXM1 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Hund, Kaninchen und Meerschweinchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für FOXM1 Antikörper (Middle Region) (ABIN501829)

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FOXM1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: ANRSLTEGLV LDTMNDSLSK ILLDISFPGL DEDPLGPDNI NWSQFIPELQ

Homologie: Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXM1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 763 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FOXM1 Antikörper (ABIN501829)

Hu, Liu, Zhang, Lou, Huang, Chen, Shen, Gao, Gong, Zhou, Dai, Zeng, He: "LXR?-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells." in: Oncogene, Vol. 33, Issue 22, pp. 2888-97, (2014) (PubMed).

Details zu FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Andere Bezeichnung: FOXM1

Hintergrund: This protein acts as a Transcriptional activatory factor. May play a role in the control of cell proliferation.
Alias Symbols: FKHL16, FOXM1B, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TGT3, TRIDENT
Protein Interaction Partner: SMAD3, FZR1, SUMO1, UBE2I, SP1, CDK2, CCNE1, BANP, OS9, HSP90AA1, CDK6, CDK4, DHX29, ACAT1, CDC27, UBC, BCL6, SUMO2, RB1, CREBBP, CDC25B, CDK1, CCNB1, ZBTB3, CHEK2, STAT3, CDH1, CENPF,
Protein Size: 763

Molekulargewicht: 84 kDa

Gen-ID: 2305

NCBI Accession: NM_021953, NP_068772

UniProt: Q08050

Pathways: Positive Regulation of Response to DNA Damage Stimulus