GRHL3 Antikörper (C-Term)

Produktnummer ABIN2781145

Der Kaninchen Polyklonal Anti-GRHL3-Antikörper wurde für WB und IHC validiert. Er ist geeignet, GRHL3 in Proben von Human, Maus, Hund, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Schwein zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für GRHL3 Antikörper (C-Term) (ABIN2781145)

Target: GRHL3 (Grainyhead-Like 3 (GRHL3))

Reaktivität: Human, Maus, Hund, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRHL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GRHL3 Antikörper

Bindungsspezifität: C-Term

Sequenz: EEVFDALMLK TPDLKGLRNA ISEKYGFPEE NIYKVYKKCK RGILVNMDNN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GRHL3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GRHL3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 509 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GRHL3 Antikörper (ABIN2781145)

Darido, Georgy, Wilanowski, Dworkin, Auden, Zhao, Rank, Srivastava, Finlay, Papenfuss, Pandolfi, Pearson, Jane: "Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis." in: Cancer cell, Vol. 20, Issue 5, pp. 635-48, (2011) (PubMed).

Details zu GRHL3

Target: GRHL3 (Grainyhead-Like 3 (GRHL3))

Andere Bezeichnung: GRHL3

Hintergrund: GRHL3 is a member of the grainyhead family of transcription factors. GRHL3 interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.
Alias Symbols: SOM, TFCP2L4
Protein Interaction Partner: PRMT6, PRMT5, PRMT1, GRHL1, GRHL3, GRHL2,
Protein Size: 509

Molekulargewicht: 57 kDa

Gen-ID: 57822

NCBI Accession: NM_198174, NP_937817