AHRR Antikörper (Middle Region)

Produktnummer ABIN2781113

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch AHRR in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Pferd, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für AHRR Antikörper (Middle Region) (ABIN2781113)

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AHRR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AHRR Antikörper

Bindungsspezifität: Middle Region

Sequenz: LPQSEPPHQL CARGRGEQSC TCRAAEAAPV VKREPLDSPQ WATHSQGMVP

Homologie: Cow: 82%, Dog: 85%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Mouse: 91%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against AHRR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AHRR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 719 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AHRR

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Andere Bezeichnung: AHRR

Hintergrund: Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. AHRR represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, AHRR can bind to nuclear factor kappa-B.Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. The protein encoded by this gene represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa-B. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AHH, AHHR, KIAA1234, MGC167813, MGC176630, bHLHe77
Protein Interaction Partner: ANKRA2, HDAC5, HDAC4, ESR1, ARNT,
Protein Size: 719

Molekulargewicht: 78 kDa

Gen-ID: 57491

NCBI Accession: NM_020731, NP_065782

UniProt: A9YTQ3

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha