GATAD2B Antikörper (N-Term)

Produktnummer ABIN2781110

Der Kaninchen Polyklonal anti-GATAD2B Antikörper (ABIN2781110) detektiert spezifisch GATAD2B in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für GATAD2B Antikörper (N-Term) (ABIN2781110)

Target: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATAD2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GATAD2B Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GATAD2B Antibody - N-terminal region

Sequenz: MDRMTEDALR LNLLKRSLDP ADERDDVLAK RLKMEGHEAM ERLKMLALLK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GATAD2B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GATAD2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101381

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GATAD2B

Target: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Andere Bezeichnung: GATAD2B

Hintergrund:

Background Information: Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.

Gene Name: GATA zinc finger domain containing 2B

Alternative Symbols: p68, GANDS, MRD18, P66beta

Protein Name: Transcriptional repressor p66-beta

Molekulargewicht: 65kDa

Gen-ID: 57459

NCBI Accession: NP_065750

UniProt: Q8WXI9