CBX4 Antikörper (Middle Region)

Produktnummer ABIN2781104

Der Kaninchen Polyklonal anti-CBX4 Antikörper (ABIN2781104) detektiert spezifisch CBX4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Pferd.

Kurzübersicht für CBX4 Antikörper (Middle Region) (ABIN2781104)

Target: CBX4 (Chromobox Homolog 4 (CBX4))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CBX4 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: CBX4 Antibody - middle region

Sequenz: KWRGWSPKYN TWEPEENILD PRLLIAFQNR ERQEQLMGYR KRGPKPKPLV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CBX4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CBX4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39421-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CBX4

Target: CBX4 (Chromobox Homolog 4 (CBX4))

Andere Bezeichnung: CBX4

Hintergrund:

Background Information: CBX4 is an E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. It is involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. It monosumoylates ZNF131.

Gene Name: chromobox homolog 8

Alternative Symbols: PC2, NBP16

Protein Name: E3 SUMO-protein ligase CBX4

Molekulargewicht: 31kDa

Gen-ID: 8535

UniProt: O00257