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MNT Antikörper (N-Term)

Dieses Anti-MNT-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MNT in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Schwein und Saccharomyces cerevisiae.
Produktnummer ABIN2781100

Kurzübersicht für MNT Antikörper (N-Term) (ABIN2781100)

Target

Alle MNT Antikörper anzeigen
MNT (MNT, MAX Dimerization Protein (MNT))

Reaktivität

  • 23
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Schwein, Saccharomyces cerevisiae

Wirt

  • 21
  • 2
  • 1
Kaninchen

Klonalität

  • 23
  • 1
Polyklonal

Konjugat

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MNT Antikörper ist unkonjugiert

Applikation

  • 17
  • 8
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    SIETLLEAAR FLEWQAQQQQ RAREEQERLR LEQEREQEQK KANSLARLAH

    Homologie

    Cow: 93%, Dog: 93%, Horse: 80%, Human: 100%, Mouse: 93%, Pig: 80%, Rabbit: 93%, Rat: 93%, Yeast: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against MNT. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human MNT
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 582 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    MNT (MNT, MAX Dimerization Protein (MNT))

    Andere Bezeichnung

    MNT

    Hintergrund

    The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MAD6, MXD6, ROX, bHLHd3
    Protein Interaction Partner: Dlg4, ELAVL1, CEBPA, MAX, MAD1L1, MYC, HDAC1, SIN3A, MNT, MLX, HMGB1,
    Protein Size: 582

    Molekulargewicht

    62 kDa

    Gen-ID

    4335

    NCBI Accession

    NM_020310, NP_064706

    UniProt

    Q99583

    Pathways

    Chromatin Binding, Regulation of Muscle Cell Differentiation
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