RRN3 Antikörper (Middle Region)
Kurzübersicht für RRN3 Antikörper (Middle Region) (ABIN2781066)
Target
Alle RRN3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- DPIYQVWEDM SAEELQEFKK PMKKDIVEDE DDDFLKGEVP QNDTVIGITP
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Homologie
- Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against RRN3. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RRN3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 651 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene." in: BMC molecular biology, Vol. 8, pp. 109, (2008) (PubMed).
: "
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Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene." in: BMC molecular biology, Vol. 8, pp. 109, (2008) (PubMed).
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- RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))
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Andere Bezeichnung
- RRN3
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Hintergrund
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RRN3 is RNA polymerase I-specific transcription initiation factor. Phosphorylation of RRN3 by MAPK cascades links cell signaling with the control of gene expression, namely results in rRNA synthesis in turn cell growth.
Alias Symbols: DKFZp566E104, MGC104238, TIFIA, A-270G1.2
Protein Interaction Partner: UBC, ACTA1, Polr1e, POLR1B, EIF3L, NMI, RBM15, UBD, Trim28, ELAVL1, TAF1D, POLR1A, MYO1C, TAF1C, TAF1B, TAF1A, UBTF, TBP, PPP2R2A, CDK2, CCNE1, RIBIN, ACTB,
Protein Size: 651 -
Molekulargewicht
- 74 kDa
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Gen-ID
- 54700
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NCBI Accession
- NM_018427, NP_060897
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UniProt
- Q9NYV6
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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