ZNF446 Antikörper (C-Term)

Produktnummer ABIN2781046

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ZNF446 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Meerschweinchen, Hund, Rind (Kuh), Pferd und Kaninchen.

Kurzübersicht für ZNF446 Antikörper (C-Term) (ABIN2781046)

Target: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Hund, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF446 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZNF446 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ZNF446 Antibody - C-terminal region

Sequenz: SYPCEECGCS FSWKSQLVIH RKSHTGQRRH FCSDCGRAFD WKSQLVIHRK

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ZNF446. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF446

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8116642

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ZNF446

Target: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Andere Bezeichnung: ZNF446

Hintergrund:

Background Information: ZNF446 contains a KRAB and three C(2)H(2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-1, suggesting that the ZNF446 protein may act as a transcriptional repressor in mitogen-activated protein kinase (MAPK) signaling pathway to mediate cellular functions.

Gene Name: Zinc finger protein 446

Alternative Symbols: ZSCAN30, ZSCAN52, ZKSCAN20

Protein Name: Zinc finger protein 446

Molekulargewicht: 49kDa

Gen-ID: 55663

NCBI Accession: NP_060378

UniProt: Q9NWS9