GTF2IRD1 Antikörper (C-Term)

Produktnummer ABIN2781010

Dieses Anti-GTF2IRD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GTF2IRD1 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für GTF2IRD1 Antikörper (C-Term) (ABIN2781010)

Target: GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2IRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GTF2IRD1 Antikörper

Bindungsspezifität: C-Term

Sequenz: VIINQLQPFA EICNDAKVPA KDSSIPKRKR KRVSEGNSVS SSSSSSSSSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against GTF2IRD1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2IRD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 959 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GTF2IRD1

Target: GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

Andere Bezeichnung: GTF2IRD1

Hintergrund: GTF2IRD1 contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. GTF2IRD1 is related to Williams-Beuren syndrome, a multisystem developmental disorder. Western blots using three different antibodies against three unique regions of this protein target confirm the same apparent molecular weight in our tests. The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants.
Alias Symbols: CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12, hMusTRD1alpha1, BEN, WBS
Protein Interaction Partner: UBC, SUMO2, USF1, HDAC3, SMAD2, EXOSC4, CDK20, PIAS2, SMAD3, NFI1,
Protein Size: 959

Molekulargewicht: 106 kDa

Gen-ID: 9569

NCBI Accession: NM_016328, NP_057412

UniProt: Q9UHL9