CoREST Antikörper (N-Term)

Produktnummer ABIN2780965

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CoREST in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.

Kurzübersicht für CoREST Antikörper (N-Term) (ABIN2780965)

Target: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Reaktivität: Human, Maus, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CoREST Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CoREST Antikörper

Bindungsspezifität: N-Term

Sequenz: MVEKGPEVSG KRRGRNNAAA SASAAAASAA ASAACASPAA TAASGAAASS

Homologie: Human: 100%, Mouse: 100%, Zebrafish: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against RCOR1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RCOR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 482 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CoREST Antikörper (ABIN2780965)

Packer, Xing, Harper, Jones, Davidson: "The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 53, pp. 14341-6, (2009) (PubMed).

Details zu CoREST

Target: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Andere Bezeichnung: RCOR1

Hintergrund: RCOR1 is a functional corepressor required for regulation of neural-specific gene expression.The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.[supplied by OMIM].
Alias Symbols: COREST, KIAA0071, RCOR
Protein Interaction Partner: HDAC1, UBC, KDM1A, HDAC2, HDAC3, NPM1, MTA3, TP53BP1, NR2C1, TCF3, HMG20B, RCOR1, SNAI1, SUMO2, Dynll1, HIST3H3, TAL1, GFI1, GFI1B, MED28, OBFC1, SUB1, MED12, TRIP4, BCL3, ESCO2, SERPINH1, ZNF217, EMD, CTBP1, RL2, NR2E1, REST, HIST1H3A, SMARCE1, SMARCC2,
Protein Size: 482

Molekulargewicht: 53 kDa

Gen-ID: 23186

NCBI Accession: NM_015156, NP_055971

UniProt: Q9UKL0

Pathways: Regulation of Hormone Metabolic Process, Chromatin Binding