IKZF3 Antikörper (C-Term)
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- Target Alle IKZF3 Antikörper anzeigen
- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IKZF3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LDYVMFTIHM GCHGFRDPFE CNMCGYRSHD RYEFSSHIAR GEHRALLK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against IKZF3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human IKZF3
- Top Product
- Discover our top product IKZF3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 509 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
- Andere Bezeichnung
- IKZF3 (IKZF3 Produkte)
- Synonyme
- AIO antikoerper, AIOLOS antikoerper, ZNFN1A3 antikoerper, aio antikoerper, aiolos antikoerper, znfn1a3 antikoerper, IKZF3 antikoerper, 5830411O07Rik antikoerper, Aiolos antikoerper, Zfpn1a3 antikoerper, Znfn1a3 antikoerper, IKAROS family zinc finger 3 antikoerper, IKAROS family zinc finger 3 L homeolog antikoerper, IKZF3 antikoerper, ikzf3.L antikoerper, Ikzf3 antikoerper
- Hintergrund
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IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Alias Symbols: AIOLOS, ZNFN1A3, AIO
Protein Interaction Partner: STAMBPL1, EXOSC5, LGALS14, CABP5, PCID2, RCOR3, TBC1D22B, FANCL, MAGOHB, C1orf109, OAZ3, SPG21, CHCHD2, OSGIN1, POLM, PPP1R16B, ABLIM3, IKZF3, NEK6, FARS2, MRPL28, KAT5, BCAS2, AKAP9, FAM115A, EMC2, POLR1C, STX11, STK16, RAD51D, PSMA1, PRKAB2, PRKAA1, PIN
Protein Size: 509 - Molekulargewicht
- 58 kDa
- Gen-ID
- 22806
- NCBI Accession
- NM_012481, NP_036613
- UniProt
- Q9UKT9
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