IKZF3 Antikörper (N-Term)

Produktnummer ABIN2780886

Der Kaninchen Polyklonal anti-IKZF3 Antikörper wird verwendet zum Nachweis von IKZF3 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen und Schwein. Er wurde validiert für WB und IHC.

Kurzübersicht für IKZF3 Antikörper (N-Term) (ABIN2780886)

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IKZF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-IKZF3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: IKZF3 Antibody - N-terminal region

Sequenz: KSTQEQSVPA ESAAVLNDYS LTKSHEMENV DSGEGPANED EDIGDDSMKV

Homologie: Cow: 86%, Dog: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against IKZF3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IKZF3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102945

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IKZF3

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Andere Bezeichnung: IKZF3

Hintergrund:

Background Information: IKZF3 is a member of the Ikaros family of zinc-finger proteins. It is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Gene Name: IKAROS family zinc finger 3 (Aiolos)

Alternative Symbols: AIO, AIOLOS, ZNFN1A3

Protein Name: Zinc finger protein Aiolos

Molekulargewicht: 52kDa

Gen-ID: 22806

NCBI Accession: NP_899051

UniProt: Q9UKT9