MafF Antikörper (N-Term)

Produktnummer ABIN2780877

Der Kaninchen Polyklonal anti-MafF Antikörper wird verwendet zum Nachweis von MafF in Proben von Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für MafF Antikörper (N-Term) (ABIN2780877)

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MafF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MafF Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MAFF Antibody - N-terminal region

Sequenz: SVRELNRHLR GLSAEEVTRL KQRRRTLKNR GYAASCRVKR VCQKEELQKQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAFF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAFF

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38984-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MafF

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Andere Bezeichnung: MAFF

Hintergrund:

Background Information: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.

Gene Name: V-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)

Alternative Symbols: U-MAF, hMafF

Protein Name: Transcription factor MafF

Molekulargewicht: 18kDa

Gen-ID: 23764

NCBI Accession: NP_690617

UniProt: Q9ULX9

Pathways: Myometrial Relaxation and Contraction