MafF Antikörper (N-Term)

Produktnummer ABIN2780877

Der Kaninchen Polyklonal Anti-MafF-Antikörper wurde für WB validiert. Er ist geeignet, MafF in Proben von Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd und Kaninchen zu detektieren.

Kurzübersicht für MafF Antikörper (N-Term) (ABIN2780877)

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MafF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MafF Antikörper

Bindungsspezifität: N-Term

Sequenz: SVRELNRHLR GLSAEEVTRL KQRRRTLKNR GYAASCRVKR VCQKEELQKQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAFF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAFF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 164 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MafF

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Andere Bezeichnung: MAFF

Hintergrund: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: U-MAF, hMafF
Protein Interaction Partner: NFE2L2, PARP1, BACH2, BATF3, MAFF, NFE2L3, NFIL3, NFE2L1, MAFG, FOS, DDIT3, BACH1, ATF3, BATF2, MAFIP, OVOL1, SUMO2, GTF2A1L, HDAC5, PPARG, NR3C1, NFE2, NRF1, PSAP, PRRX1, HOXD12,
Protein Size: 164

Molekulargewicht: 18 kDa

Gen-ID: 23764

NCBI Accession: NM_152878, NP_690617

UniProt: Q9ULX9

Pathways: Myometrial Relaxation and Contraction