HBP1 Antikörper (Middle Region)

Produktnummer ABIN405189

Dieser Anti-HBP1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von HBP1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für HBP1 Antikörper (Middle Region) (ABIN405189)

Target: HBP1 (HMG Box-Containing Protein 1 (HBP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HBP1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: SVILGDRWKK MKNEERRMYT LEAKALAEEQ KRLNPDCWKR KRTNSGSQQH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against HBP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 514 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HBP1 Antikörper (ABIN405189)

Wang, Pan, Chen, Huang, Zhang: "The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression." in: Nucleic acids research, Vol. 40, Issue 3, pp. 981-95, (2012) (PubMed).

Li, Bian, Liao, Li, Zhao: "miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1." in: Breast cancer research and treatment, Vol. 126, Issue 3, pp. 565-75, (2011) (PubMed).

Details zu HBP1

Target: HBP1 (HMG Box-Containing Protein 1 (HBP1))

Andere Bezeichnung: HBP1

Hintergrund: HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4.
Alias Symbols: FLJ16340
Protein Interaction Partner: FBXW11, UBC, TMEM37, SMAD1, ZNF212, KIAA1279, EWSR1, CD2AP, EP300, CREBBP, MYC, ANKRD2, SIN3A, SAP30, TCF4, HDAC1, RBL2, RB1,
Protein Size: 514

Molekulargewicht: 58 kDa

Gen-ID: 26959

NCBI Accession: NM_012257, NP_036389

UniProt: O60381