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BRD3 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BRD3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Rind (Kuh).
Produktnummer ABIN2780846

Kurzübersicht für BRD3 Antikörper (N-Term) (ABIN2780846)

Target

Alle BRD3 Antikörper anzeigen
BRD3 (Bromodomain Containing 3 (BRD3))

Reaktivität

  • 74
  • 33
  • 12
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human, Maus, Ratte, Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh)

Wirt

  • 67
  • 7
Kaninchen

Klonalität

  • 66
  • 8
Polyklonal

Konjugat

  • 44
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BRD3 Antikörper ist unkonjugiert

Applikation

  • 56
  • 24
  • 23
  • 15
  • 13
  • 11
  • 11
  • 11
  • 8
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    MSTATTVAPA GIPATPGPVN PPPPEVSNPS KPGRKTNQLQ YMQNVVVKTL

    Homologie

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against BRD3. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human BRD3
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 556 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    BRD3 (Bromodomain Containing 3 (BRD3))

    Andere Bezeichnung

    BRD3

    Hintergrund

    This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. BRD3 is ubiquitously expressed in human adult and fetal tissues. BRD3 is markedly expressed in undifferentiated ES cells, whereas the expression was reduced upon endothelial differentiation. BRD3 plays a role in regulation of cell proliferation by allowing cells to enter the proliferative phase of the angiogenic process.BRD3 is also involved in bladder cancer.
    Alias Symbols: ORFX, RING3L
    Protein Interaction Partner: SRPK2, MYC, UBC, YEATS4, APP, SPP1, ELAVL1, MAP1LC3B, tat, BRD7,
    Protein Size: 556

    Molekulargewicht

    61 kDa

    Gen-ID

    8019

    NCBI Accession

    NM_007371

    UniProt

    Q5T1R6

    Pathways

    Chromatin Binding
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