KLF12 Antikörper (N-Term)

Produktnummer ABIN2780839

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KLF12 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für KLF12 Antikörper (N-Term) (ABIN2780839)

Target: KLF12 (Kruppel-Like Factor 12 (KLF12))

Reaktivität: Human, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KLF12 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: KLF12 Antibody - N-terminal region

Sequenz: NIHMKRKTIK NINTFENRML MLDGMPAVRV KTELLESEQG SPNVHNYPDM

Homologie: Dog: 100%, Guinea Pig: 93%, Human: 100%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against KLF12. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLF12

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38927-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu KLF12

Target: KLF12 (Kruppel-Like Factor 12 (KLF12))

Andere Bezeichnung: KLF12

Hintergrund:

Background Information: Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1.Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Kruppel-like factor 12

Alternative Symbols: AP2REP, AP-2rep, HSPC122

Protein Name: Krueppel-like factor 12

Molekulargewicht: 44kDa

Gen-ID: 11278

NCBI Accession: NP_009180

UniProt: Q9Y4X4