RORB Antikörper (C-Term)

Produktnummer ABIN2780814

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RORB in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schaf, Kaninchen und Meerschweinchen.

Kurzübersicht für RORB Antikörper (C-Term) (ABIN2780814)

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schaf, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RORB Antikörper

Bindungsspezifität: C-Term

Sequenz: KNHLDDETLA KLIAKIPTIT AVCNLHGEKL QVFKQSHPEI VNTLFPPLYK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RORB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RORB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 459 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RORB

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Andere Bezeichnung: RORB

Hintergrund: RORB is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NR1F2, ROR-BETA, RZRB, bA133M9.1, RZR-BETA
Protein Interaction Partner: NSD1, NCOA1, NCOA6, PNRC1, EIF3I, NRIP1, UBE2I, TNNI2, SRC, PSMC4, NPPA, MAP6, PNRC2, NRIP2, NME2, NME1,
Protein Size: 459

Molekulargewicht: 52 kDa

Gen-ID: 6096

NCBI Accession: NM_006914, NP_008845

UniProt: Q98934

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway