LZTR1 Antikörper (N-Term)
Kurzübersicht für LZTR1 Antikörper (N-Term) (ABIN2780806)
Target
Alle LZTR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- AGPGSTGGQI GAAALAGGAR SKVAPSVDFD HSCSDSVEYL TLNFGPFETV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against LZTR1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human LZTR1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 840 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LZTR1 (Leucine-Zipper-Like Transcription Regulator 1 (LZTR1))
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Andere Bezeichnung
- LZTR1
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Hintergrund
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Leucine-zipper-like transcriptional regulator 1(LZTR1) is belived to be a DNA-binding protein and transcriptional regulator based on its predicted structural characteristics. The transcript is present in several essential fetal organs and is hemizygously deleted in some DiGeorge syndrome patients. LZTR1 is thought to play a critical role in embryogenesis.This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.
Alias Symbols: LZTR-1, MGC21205, TCFL2
Protein Interaction Partner: LZTR1, TUBGCP4, CUL3, UBC, CNOT6L, ZNF584, ZNF714, ASB12, FANK1, TRIM5, KDM2B, L3MBTL3, POLR1B, ANKRD53, EHMT1, E2F8, PAPOLG, ZNF490, SND1, AATF, ZNF451, ZZZ3, SCMH1, ZBTB1, WWP1, RAI1, CEBPZ, SUGP2, NR1H3, CHAF1A, MED16, HDAC4, MED7, RUVBL1, IKBKG, ZNF17
Protein Size: 840 -
Molekulargewicht
- 95 kDa
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Gen-ID
- 8216
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NCBI Accession
- NM_006767, NP_006758
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UniProt
- Q8N653
Target
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