PEG3 Antikörper (C-Term)
Kurzübersicht für PEG3 Antikörper (C-Term) (ABIN2780754)
Target
Alle PEG3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Sequenz
- FGECSGYIER ASTSTGGANQ ADEKYFKCDV CGQLFNDRLS LARHQNTHTG
-
Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against PEG3. It was validated on Western Blot using a cell lysate as a positive control.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human PEG3
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 1588 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- PEG3 (Paternally Expressed 3 (PEG3))
-
Andere Bezeichnung
- PEG3
-
Hintergrund
-
PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.
Alias Symbols: PW1, ZNF904, ZSCAN24
Protein Interaction Partner: PEG3, ALB, USP7, TRAF2, SIAH2, SIAH1, BRCA1,
Protein Size: 1588 -
Molekulargewicht
- 181 kDa
-
Gen-ID
- 5178
-
NCBI Accession
- NM_006210, NP_006201
-
UniProt
- Q9GZU2
Target
-