ZBTB16 Antikörper (C-Term)
Kurzübersicht für ZBTB16 Antikörper (C-Term) (ABIN2780737)
Target
Alle ZBTB16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- GASPYQCTIC TEYCPSLSSM QKHMKGHKPE EIPPDWRIEK TYLYLCYV
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ZBTB16. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human ZBTB16
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 673 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "An unusual haplotype structure on human chromosome 8p23 derived from the inversion polymorphism." in: Human mutation, Vol. 29, Issue 10, pp. 1209-16, (2008) (PubMed).
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: "An unusual haplotype structure on human chromosome 8p23 derived from the inversion polymorphism." in: Human mutation, Vol. 29, Issue 10, pp. 1209-16, (2008) (PubMed).
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- ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))
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Andere Bezeichnung
- ZBTB16
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Hintergrund
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ZBTB16 is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
Alias Symbols: PLZF, ZNF145
Protein Interaction Partner: KRT40, SH2D4A, TRIM54, LAMTOR5, IL32, ZBTB16, SUMO2, PRKCE, GOLGA2, HDAC1, CEBPA, EP300, MBD3, SIN3A, CBX5, NCOR1, MTA2, HDAC3, TP53, NCOR2, ZNF281, TAB2, SMAD3, CFH, ADAMTS4, HOXA1, CASP3, ATP7B, PARP1, TIMP1, FSHR, EEF1A1, TNK2, ATP6AP2, HDAC4, Gne, Gna
Protein Size: 673 -
Molekulargewicht
- 74 kDa
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Gen-ID
- 7704
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NCBI Accession
- NM_006006, NP_005997
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UniProt
- Q05516
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Pathways
- Positive Regulation of fat Cell Differentiation
Target
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