NAB2 Antikörper (C-Term)

Produktnummer ABIN2780731

Produktdetails anti-NAB2 Antikörper

Target: NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GRLSPCVPAK PPLAEFEEGL LDRCPAPGPH PALVEGRRSS VKVEAEASRQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NAB2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NAB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 525 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NAB2

Target: NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))

Andere Bezeichnung: NAB2 (NAB2 Produkte)

Synonyme: mader antikoerper, AI451907 antikoerper, MADER antikoerper, NGFI-A binding protein 2 (EGR1 binding protein 2) antikoerper, Ngfi-A binding protein 2 antikoerper, NGFI-A binding protein 2 antikoerper, nab2 antikoerper, Nab2 antikoerper, NAB2 antikoerper

Hintergrund: NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize withThis gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MADER, MGC75085
Protein Interaction Partner: AES, KRT40, ZMYND19, TGIF2LY, TCHP, CCDC33, GCC1, LENG1, SCNM1, ZBED8, TTC19, CCHCR1, NME7, RBPMS, MORF4L1, JAKMIP2, RFC5, PIN1, PHF1, NEDD9, NAB2, MDFI, MCM7, PHOSPHO2, SUMO1P1, NOTCH2NL, KRTAP10-3, KRTAP10-8, TCEANC, CWF19L2, DGCR6, MAPK3, VBP1, TLN1, S
Protein Size: 525

Molekulargewicht: 56 kDa

Gen-ID: 4665

NCBI Accession: NM_005967, NP_005958

UniProt: Q15742