MEF2D Antikörper (Middle Region)

Produktnummer ABIN2780725

Produktdetails anti-MEF2D Antikörper

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEF2D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GDGLSSPAGG SYETGDRDDG RGDFGPTLGL LRPAPEPEAE GSAVKRMRLD

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MEF2D. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MEF2D

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 521 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MEF2D

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Andere Bezeichnung: MEF2D (MEF2D Produkte)

Synonyme: sl1 antikoerper, sl-1 antikoerper, XMEF2D antikoerper, MGC145245 antikoerper, C80750 antikoerper, myocyte enhancer factor 2D antikoerper, MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) antikoerper, mef2d antikoerper, MEF2D antikoerper, Mef2d antikoerper

Hintergrund: MEF2D is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. MEF2D mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival.MEF2D plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription.MEF2D plays a critical role in the regulation of neuronal apoptosis.
Alias Symbols: DKFZp686I1536
Protein Interaction Partner: SUMO1, CDK6, ASCL1, APP, SUMO2, UBC, CABIN1, MEF2A, HDAC1, HIRA, ASH2L, KMT2D, RBBP5, MEN1, PRKACA, SENP3, HDAC4, COPS5, CARM1, PRMT5, KAT2B, HDAC3, SNCA, MAPK14, HDAC5, EP300, MAPK7, CASP7, MEF2D, MEF2C, NFATC2, SP1, YWHAQ,
Protein Size: 521

Molekulargewicht: 56 kDa

Gen-ID: 4209

NCBI Accession: NM_005920, NP_005911

UniProt: Q14814