TP53BP2 Antikörper (N-Term)
Kurzübersicht für TP53BP2 Antikörper (N-Term) (ABIN2780683)
Target
Alle TP53BP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- TLAELQEMAS RQQQQIEAQQ QLLATKEQRL KFLKQQDQRQ QQQVAEQEKL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TP53BP2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TP53BP2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 1127 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))
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Andere Bezeichnung
- TP53BP2
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Hintergrund
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TP53BP2 is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. TP53BP2 contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. TP53BP2 is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family.
Alias Symbols: BBP, 53BP2, ASPP2, P53BP2, PPP1R13A
Protein Interaction Partner: TXLNA, CWF19L2, SSX2IP, ATPAF2, ZGPAT, PLEKHN1, CCDC92, OTUB2, MTMR14, TBC1D22B, DCUN1D1, UBASH3A, PRPF31, NUTM1, HNRNPUL1, NXF1, BAIAP2, NDC80, TANK, TRAF4, LMO4, HIST1H2BC, TCL1A, ZNF26, SIAH1, PPP1CC, PPP1CB, POLR2L, GRB2, BCL2L1, BCL2, PRKAB2, UBC, AM
Protein Size: 1127 -
Molekulargewicht
- 124 kDa
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Gen-ID
- 7159
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NCBI Accession
- NM_001031685, NP_001026855
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UniProt
- Q13625
Target
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