MED26 Antikörper (N-Term)

Produktnummer ABIN2780622

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MED26 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Rind (Kuh), Hund, Kaninchen und Ratte.

Kurzübersicht für MED26 Antikörper (N-Term) (ABIN2780622)

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED26 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MED26 Antikörper

Bindungsspezifität: N-Term

Sequenz: TAAPASPQQI RDRLLQAIDP QSNIRNMVAV LEVISSLEKY PITKEALEET

Homologie: Cow: 93%, Dog: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MED26. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MED26

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 600 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MED26

Target: MED26 (Mediator Complex Subunit 26 (MED26))

Andere Bezeichnung: MED26

Hintergrund: MED26 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-261 AC024075.4 20290-20550 c 262-726 AF104253.1 1-465 727-3184 AK128435.1 1414-3871
Alias Symbols: CRSP7, CRSP70
Protein Interaction Partner: MED19, MED13, MED12, MED21, MED11, TAF8, MED8, MED30, EAF1, MED10, TAF3, MED25, MED28, ICE2, EAF2, MED29, MED9, MED18, MED15, MED31, MED4, AFF4, MED13L, ICE1, CDK19, ELL2, MED16, MED6, MED20, MED7, MED27, MED17, MED23, MED14, ELL, TAF15, TCEB3, TCEA1, TBP
Protein Size: 600

Molekulargewicht: 65 kDa

Gen-ID: 9441

NCBI Accession: NM_004831, NP_004822

UniProt: O95402

Pathways: Regulation of Lipid Metabolism by PPARalpha