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MED27 Antikörper (C-Term)

MED27 Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780582
  • Target Alle MED27 Antikörper anzeigen
    MED27 (Mediator Complex Subunit 27 (MED27))
    Bindungsspezifität
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 33
    • 16
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Rind (Kuh), Hund, Ratte, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 30
    • 4
    Kaninchen
    Klonalität
    • 32
    • 2
    Polyklonal
    Konjugat
    • 20
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MED27 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 14
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    VVRSFMTWLR SYIKLFQAPC QRCGKFLQDG LPPTWRDFRT LEAFHDTCRQ
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CRSP8. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CRSP8
    Top Product
    Discover our top product MED27 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 311 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MED27 (Mediator Complex Subunit 27 (MED27))
    Andere Bezeichnung
    CRSP8 (MED27 Produkte)
    Synonyme
    CRAP34 antikoerper, CRSP34 antikoerper, CRSP8 antikoerper, TRAP37 antikoerper, CG1245 antikoerper, Dmel\\CG1245 antikoerper, Med27 antikoerper, Trap37 antikoerper, dCRSP34 antikoerper, dCrsp34 antikoerper, dTRAP37 antikoerper, med27 antikoerper, crsp8 antikoerper, zgc:66302 antikoerper, MED27 antikoerper, DDBDRAFT_0216764 antikoerper, DDBDRAFT_0266847 antikoerper, DDB_0216764 antikoerper, DDB_0266847 antikoerper, 1500015J03Rik antikoerper, 2310042P07Rik antikoerper, AA682045 antikoerper, Crsp8 antikoerper, D2Ertd434e antikoerper, RGD1564993 antikoerper, DKFZp459I1912 antikoerper, CRSP complex subunit 8-B antikoerper, Xcrsp34 antikoerper, crap34 antikoerper, crsp34 antikoerper, crsp8-B antikoerper, med27-a antikoerper, med27-b antikoerper, trap37 antikoerper, mediator complex subunit 27 antikoerper, Mediator complex subunit 27 antikoerper, cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa antikoerper, hypothetical protein antikoerper, mediator complex subunit 27 S homeolog antikoerper, MED27 antikoerper, med27 antikoerper, crsp8 antikoerper, Med27 antikoerper, med27.S antikoerper
    Hintergrund
    He activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. CRSP8 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. CRSP8 is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
    Alias Symbols: CRSP8, CRAP34, CRSP34, TRAP37
    Protein Interaction Partner: UBC, CDK19, CDK8, MED19, ARFGAP1, MED26, SOX5, POLR2C, RBPJ, AFP, FBXW7, EPAS1, MED4, MED12, MED14, MED1, MED28, OBFC1, MED18, ZC3H13, QKI, TRIP4, TADA2A, MED9, MED30, MED8, MED22, MED10, MED29,
    Protein Size: 311
    Molekulargewicht
    35 kDa
    Gen-ID
    9442
    NCBI Accession
    NM_004269, NP_004260
    UniProt
    Q6P2C8
    Pathways
    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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