SAP30 Antikörper (Middle Region)

Produktnummer ABIN2780556

Dieses Anti-SAP30-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SAP30 in WB. Geeignet für Human, Maus, Kaninchen, Rind (Kuh), Hund, Ratte, Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für SAP30 Antikörper (Middle Region) (ABIN2780556)

Target: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Reaktivität: Human, Maus, Kaninchen, Rind (Kuh), Hund, Ratte, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAP30 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SAP30 Antikörper

Bindungsspezifität: Middle Region

Sequenz: YQLQVNTLRR YKRHFKLPTR PGLNKAQLVE IVGCHFRSIP VNEKDTLTYF

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SAP30. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SAP30

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 220 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SAP30

Target: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Andere Bezeichnung: SAP30

Hintergrund: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
Alias Symbols: -
Protein Interaction Partner: HDAC3, CUL4B, DDB1, HDAC1, SIN3A, UBC, HDAC2, BRMS1L, ING1, ARID4A, SAMSN1, ZNF395, UBASH3B, RBBP7, RBBP4, CHD4, ALL1, TAF6, SMARCA2, SAP25, RBP1, HIST2H2BE, PCBD1, ID3, SAP30BP, HIST2H4A, HBP1, HIST1H2AL, BRMS1, CIR1, HIST3H3, NCOR1, NCOR2, MXD1, YY1, HT
Protein Size: 220

Molekulargewicht: 23 kDa

Gen-ID: 8819

NCBI Accession: NM_003864, NP_003855

UniProt: O75446