ZNF76 Antikörper (N-Term)
Kurzübersicht für ZNF76 Antikörper (N-Term) (ABIN2780514)
Target
Alle ZNF76 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Sequenz
- LSDGTTAYVQ QAVKGEKLLE GQVIQLEDGT TAYIHQVTVQ KEALSFEDGQ
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against ZNF76. It was validated on Western Blot using a cell lysate as a positive control.
-
Aufreinigung
- Protein A purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF76
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 570 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- ZNF76 (Zinc Finger Protein 76 (Expressed in Testis) (ZNF76))
-
Andere Bezeichnung
- ZNF76
-
Hintergrund
-
ZNF76 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF76 is a general transcription repressor targeting TATA-binding protein (TBP), through a process regulated by sumoylation. ZNF76 interacts with TBP through both its N and C termini, and both regions are required for ZNF76 to exert its inhibitory function on p53-mediated transactivation. As a TBP-interacting transcriptional modulator, ZNF76 is also regulated by alternative splicing.
Alias Symbols: ZNF523, Zfp523, D6S229E
Protein Interaction Partner: SMAD1, UBC, TBP, HDAC1, EP300, CAND1, ELAVL1, Pias1,
Protein Size: 570 -
Molekulargewicht
- 62 kDa
-
Gen-ID
- 7629
-
NCBI Accession
- NM_003427, NP_003418
-
UniProt
- P36508
Target
-