TEF Antikörper (N-Term)

Produktnummer ABIN2780494

Dieses Anti-TEF-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TEF in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Pferd, Meerschweinchen und Ziege.

Kurzübersicht für TEF Antikörper (N-Term) (ABIN2780494)

Target: TEF (Thyrotrophic Embryonic Factor (TEF))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Pferd, Meerschweinchen, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TEF Antikörper

Bindungsspezifität: N-Term

Sequenz: PVDPQAGPGP GPGRAAGERG LSGSFPLVLK KLMENPPREA RLDKEKGKEK

Homologie: Cow: 93%, Dog: 93%, Goat: 91%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TEF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TEF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 303 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TEF

Target: TEF (Thyrotrophic Embryonic Factor (TEF))

Andere Bezeichnung: TEF

Hintergrund: TEF (thyrotroph embryonic factor) is a member of the PAR bZip (proline and acidic amino acid-rich basic leucine zipper) transcription factor family. It accumulates with robust circadian rhythms in tissues with high amplitudes of clock gene expression.Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP), VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties.
Alias Symbols: -
Protein Interaction Partner: MRPL28, DBP,
Protein Size: 303

Molekulargewicht: 33 kDa

Gen-ID: 7008

NCBI Accession: NM_003216, NP_003207

UniProt: Q10587