TEAD4 Antikörper (C-Term)

Produktnummer ABIN2780491

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TEAD4 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.

Kurzübersicht für TEAD4 Antikörper (C-Term) (ABIN2780491)

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEAD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TEAD4 Antikörper

Bindungsspezifität: C-Term

Sequenz: MMNSVLENFT ILQVVTNRDT QETLLCIAYV FEVSASEHGA QHHIYRLVKE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TEAD4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TEAD4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 434 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TEAD4 Antikörper (ABIN2780491)

Ribas, Moncaut, Siligan, Taylor, Cross, Rigby, Carvajal: "Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments." in: Developmental biology, Vol. 355, Issue 2, pp. 372-80, (2011) (PubMed).

Details zu TEAD4

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Andere Bezeichnung: TEAD4

Hintergrund: TEAD4 is a member of the transcriptional enhancer factor (TEF) family. The family members contain the TEA/ATTS DNA-binding domain. TEAD4 is preferentially expressed in skeletal muscle, and binds to the M-CAT regulatory element which directs muscle-specific gene expression. TEAD4 is encoded through the use of a non-AUG (TTG) translation initiation codon. This gene encodes a member of the transcriptional enhancer factor (TEF) family. The family members contain the TEA/ATTS DNA-binding domain. This member is preferentially expressed in skeletal muscle, and binds to the M-CAT regulatory element which directs muscle-specific gene expression. The protein is encoded through the use of a non-AUG (TTG) translation initiation codon. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: TEF3, RTEF1, TEF-3, EFTR-2, TEFR-1, TCF13L1, hRTEF-1B
Protein Interaction Partner: CCDC172, SSX2IP, LZTS2, CEP70, CEP55, RABGEF1, CCNDBP1, KIAA0753, PNMA1, TRAF1, VPS52, TRIM27, GOLGA2, UBC, SUMO2, CCDC85B, WWTR1, YAP1, VGLL1, MYH7,
Protein Size: 434

Molekulargewicht: 48 kDa

Gen-ID: 7004

NCBI Accession: NM_003213, NP_003204

UniProt: Q96BK2

Pathways: Regulation of Lipid Metabolism by PPARalpha