Spt6 Antikörper (C-Term)
Kurzübersicht für Spt6 Antikörper (C-Term) (ABIN2780484)
Target
Alle Spt6 (SUPT6H) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- RQQQPKSNSH AAIDWGKMAE QWLQEKEAER RKQKQRLTPR PSPSPMIEST
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SUPT6H. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SUPT6H
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Spt6 (SUPT6H) (Suppressor of Ty 6 Homolog (SUPT6H))
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Andere Bezeichnung
- SUPT6H
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Hintergrund
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SUPT6H may be functionally analogous to SPT6 and emb-5 and may therefore regulate transcription through establishment or maintenance of chromatin structure. Spt6 may also participates in the regulation of transcription by RNA polymerase II (RNAPII). Human Spt6 (hSpt6) is a classic transcription elongation factor that enhances the rate of RNAPII elongation. HSpt6 is capable of stimulating transcription elongation both individually and in concert with DRB sensitivity-inducing factor (DSIF).
Alias Symbols: SPT6, SPT6H, emb-5
Protein Interaction Partner: CEP76, HAUS2, CEP250, TUBGCP3, CEP57, VCP, TUBG1, TP53, EMD, CDKN1A, UBC, EED, BMI1, POLR2C, ERBB2, CSNK2A1, BRCA1, MDC1, PAAF1, SIRT7, SUMO2, POLR2A, IWS1, WDR48, TCEA1,
Protein Size: 1726 -
Molekulargewicht
- 199 kDa
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Gen-ID
- 6830
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NCBI Accession
- NM_003170, NP_003161
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UniProt
- Q7KZ85
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Pathways
- Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response
Target
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