RFX1 Antikörper (N-Term)

Produktnummer ABIN2780453

Dieses Anti-RFX1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RFX1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Schwein, Pferd und Kaninchen.

Kurzübersicht für RFX1 Antikörper (N-Term) (ABIN2780453)

Target: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Schwein, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RFX1 Antikörper

Bindungsspezifität: N-Term

Sequenz: PQPPQPPTAA ATPQPQYVTE LQSPQPQAQP PGGQKQYVTE LPAVPAPSQP

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RFX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RFX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 979 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RFX1

Target: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Andere Bezeichnung: RFX1

Hintergrund: This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX1 is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EF-C, EFC, RFX
Protein Interaction Partner: SOX2, SMAD9, SMAD4, SMAD1, NOTCH1, Cebpb, NCOA3, HDAC1, NFIC, NFIB, TADA3, RFX3, MAGED1, ABL1, NFIX, HMGB1, HIVEP2, RFX2, ADD1,
Protein Size: 979

Molekulargewicht: 105 kDa

Gen-ID: 5989

NCBI Accession: NM_002918, NP_002909

UniProt: P22670

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response