c-Rel Antikörper (Middle Region)

Produktnummer ABIN2780452

Der Kaninchen Polyklonal Anti-c-Rel-Antikörper wurde für WB validiert. Er ist geeignet, c-Rel in Proben von Human, Hund, Pferd, Rind (Kuh), Kaninchen und Schwein zu detektieren.

Kurzübersicht für c-Rel Antikörper (Middle Region) (ABIN2780452)

Target: c-Rel (REL proto-oncogene (c-Rel))

Reaktivität: Human, Hund, Pferd, Rind (Kuh), Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser c-Rel Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-c-Rel Antikörper

Bindungsspezifität: Middle Region

Sequenz: CADNSMINES GPSNSTNPNS HGFVQDSQYS GIGSMQNEQL SDSFPYEFFQ

Homologie: Cow: 91%, Dog: 77%, Horse: 85%, Human: 100%, Pig: 93%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against REL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human REL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 619 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu c-Rel

Target: c-Rel (REL proto-oncogene (c-Rel))

Andere Bezeichnung: REL

Hintergrund: REL is a member of the Rel/NFKB family, which also includes RELA, RELB, NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor. The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-174 CN414487.1 2-175 175-2323 X75042.1 128-2276 2324-2457 BX111941.1 575-708 2458-2592 AA279919.1 1-135 c
Alias Symbols: C-Rel
Protein Interaction Partner: NFKB2, REXO1L6P, C12orf75, TRIM74, RAB41, BARHL2, SEC14L4, NUDT14, ZDHHC24, NEIL2, CPNE2, C9orf72, STRA13, TTC21A, FUT11, ZNF564, ZNF550, PATE1, TSTD2, ZNF417, ZNF572, GLYCTK, EGLN3, RIPPLY1, ZNF765, ATPAF2, SLC39A13, BMF, KRTAP9-4, CEP19, VPS25, MIEN1, P
Protein Size: 619

Molekulargewicht: 68 kDa

Gen-ID: 5966

NCBI Accession: NM_002908, NP_002899

UniProt: Q04864