MXD1 Antikörper (N-Term)

Produktnummer ABIN2780418

Produktdetails anti-MXD1 Antikörper

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Pferd, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MXD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAAAVRMNIQ MLLEAADYLE RREREAEHGY ASMLPYNNKD RDALKRRNKS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MXD1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MXD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 221 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MXD1

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Andere Bezeichnung: MXD1 (MXD1 Produkte)

Synonyme: MXD1 antikoerper, si:dkey-202n14.4 antikoerper, xmad1 antikoerper, BHLHC58 antikoerper, MAD antikoerper, MAD1 antikoerper, AW122478 antikoerper, Mad antikoerper, Mad1 antikoerper, Mad-1 antikoerper, MAX dimerization protein 1 antikoerper, MAX dimerization protein 1 L homeolog antikoerper, max dimerization protein 1 antikoerper, MXD1 antikoerper, mxd1 antikoerper, mxd1.L antikoerper, Mxd1 antikoerper

Hintergrund: MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. MXD1 competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor.MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. This protein competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAD, MAD1, MGC104659, BHLHC58
Protein Interaction Partner: HDAC2, MAX, VDR, APP, BIRC2, RPS6KB1, RPS6KA1, AKT1, SIN3A, KDM5A, SIN3B, PRAM1, SMC3, SAP30, MXD1, MYC, CD2, MYCL, MYCN, PML, MLX, HDAC1,
Protein Size: 221

Molekulargewicht: 25 kDa

Gen-ID: 4084

NCBI Accession: NM_002357, NP_002348

UniProt: Q0VFI9