TADA2L Antikörper (Middle Region)

Produktnummer ABIN2780370

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TADA2L in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.

Kurzübersicht für TADA2L Antikörper (Middle Region) (ABIN2780370)

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TADA2L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TADA2L Antikörper

Bindungsspezifität: Middle Region

Sequenz: LEYKSALLNE CNKQGGLRLA QARALIKIDV NKTRKIYDFL IREGYITKG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TADA2L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TADA2L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 443 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TADA2L Antikörper (ABIN2780370)

Thompson, Yang, Power, Hufschmid, Beveridge, Reid, Ng, Armson, Ryan: "Identification of zoonotic Giardia genotypes in marsupials in Australia." in: Experimental parasitology, Vol. 120, Issue 1, pp. 88-93, (2008) (PubMed).

Details zu TADA2L

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Andere Bezeichnung: TADA2L

Hintergrund: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: ADA2, FLJ12705, KL04P, hADA2, ADA2A, TADA2L
Protein Interaction Partner: MFAP1, MAGOH, KPNA2, FBF1, PRPF31, PPP1R16B, ZFYVE26, SF3A3, FARS2, MTX2, EIF4E2, FAM127C, KLHL38, TTC9C, ZNF564, TEKT4, LOC149950, KLC4, TTC23, GPSM3, CDCA7L, C1orf109, CCHCR1, PRKAB2, ARNT2, USP22, TADA3, HNF4A, LYN, HSP90AA1, KAT2B, MCPH1, PAXIP1, SUPT
Protein Size: 443

Molekulargewicht: 51 kDa

Gen-ID: 6871

NCBI Accession: NM_001488, NP_001479

UniProt: O75478

Pathways: Chromatin Binding