Elf4 Antikörper (N-Term)

Produktnummer ABIN2780359

Produktdetails anti-Elf4 Antikörper

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Elf4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAITLQPSDL IFEFASNGMD DDIHQLEDPS VFPAVIVEQV PYPDLLHLYS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ELF4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ELF4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 663 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Elf4

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Andere Bezeichnung: ELF4 (Elf4 Produkte)

Synonyme: ELF4 antikoerper, RGD1560743 antikoerper, ELFR antikoerper, MEF antikoerper, AV314029 antikoerper, BC042423 antikoerper, ENSMUSG00000053512 antikoerper, Gm9907 antikoerper, Mef antikoerper, E74 like ETS transcription factor 4 antikoerper, E74-like factor 4 (ets domain transcription factor) antikoerper, ELF4 antikoerper, Elf4 antikoerper

Hintergrund: ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.
Alias Symbols: MEF, ELFR
Protein Interaction Partner: NPM1, SET, CASP4, UBC, PML, SKP2, KDM5B, FBXO4, FBXO7, UBB, RUNX1,
Protein Size: 663

Molekulargewicht: 71 kDa

Gen-ID: 2000

NCBI Accession: NM_001421, NP_001412

UniProt: Q99607

Pathways: Positive Regulation of Endopeptidase Activity