PRDM1 Antikörper (N-Term)

Produktnummer ABIN2780353

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PRDM1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für PRDM1 Antikörper (N-Term) (ABIN2780353)

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PRDM1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MKMDMEDADM TLWTEAEFEE KCTYIVNDHP WDSGADGGTS VQAEASLPRN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRDM1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 789 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PRDM1

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Andere Bezeichnung: PRDM1

Hintergrund: PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Alias Symbols: BLIMP1, PRDI-BF1
Protein Interaction Partner: PRMT5, SENP1, EHMT2, PIAS1, SUMO1, IRF2, IRF1, HDAC2, HDAC1, HIST1H1A, MS4A1, HSP90AA1, ATXN1, ELAVL1, KDM1A, IRF4, TLE2, TLE1, AES, PRMT7, HIST2H3A,
Protein Size: 789

Molekulargewicht: 88 kDa

Gen-ID: 639

NCBI Accession: NM_001198, NP_001189

UniProt: O75626

Pathways: Regulation of Muscle Cell Differentiation