Fibrillin 1 Antikörper (N-Term)

Produktnummer ABIN2780329

Der Kaninchen Polyklonal Anti-Fibrillin 1-Antikörper wurde für WB validiert. Er ist geeignet, Fibrillin 1 in Proben von Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Pferd, Meerschweinchen und Kaninchen zu detektieren.

Kurzübersicht für Fibrillin 1 Antikörper (N-Term) (ABIN2780329)

Target: Fibrillin 1 (FBN1)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibrillin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Fibrillin 1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MRRGRLLEIA LGFTVLLASY TSHGADANLE AGNVKETRAS RAKRRGGGGH

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FBN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 195 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Fibrillin 1

Target: Fibrillin 1 (FBN1)

Andere Bezeichnung: FBN1

Hintergrund: FBN1 is a member of the fibrillin family. FBN1 is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.
Alias Symbols: FBN, SGS, WMS, MASS, MFS1, OCTD, SSKS, WMS2, ACMICD, GPHYSD2
Protein Interaction Partner: UBC, SPRY2, ATXN7, MYOC, MFAP5, MFAP2, LTBP1, HSPG2, FBLN2, ELN, DCN, FBN2, VCAN, CALR,
Protein Size: 195

Molekulargewicht: 21 kDa

Gen-ID: 2200

NCBI Accession: NM_000138

UniProt: Q75N89

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom