SP110 Antikörper (Middle Region)

Produktnummer ABIN2780261

Der Kaninchen Polyklonal anti-SP110 Antikörper (ABIN2780261) detektiert spezifisch SP110 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Pferd.

Kurzübersicht für SP110 Antikörper (Middle Region) (ABIN2780261)

Target: SP110 (SP110 Nuclear Body Protein (SP110))

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SP110 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SP110 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: SP110 Antibody - middle region

Sequenz: LKAYCHPQSS FFTGIPFNIR DYGEPFQEAM WLDLVKERLI TEMYTVAWFV

Homologie: Horse: 75%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SP110. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SP110

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37795-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SP110

Target: SP110 (SP110 Nuclear Body Protein (SP110))

Andere Bezeichnung: SP110

Hintergrund:

Background Information: The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. SP110 is a member of the SP100/SP140 family of nuclear body proteins and is a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Gene Name: SP110 nuclear body protein

Alternative Symbols: IPR1, VODI, IFI41, IFI75

Protein Name: Sp110 nuclear body protein

Molekulargewicht: 81kDa

Gen-ID: 3431

NCBI Accession: NP_536349

UniProt: Q9HB58